Publications

2025

A capsular polysaccharide from a member of the healthy human microbiota activates a Lag-3-NK cell axis to restrain colon cancer and augment immunotherapy

Weis AM, Bauer K, Tang WW, Stephen-Victor E, Bell R, Brown DG, Ekiz HA, Tran V, Klag KA, Swanson EA, Greenewood M, Barrios L, Hill JH, Ost KS, Gigic B, Schneider M, Ose J, Hardikar S, Toriola AT, Shibata D, Li CI, Figueiredo JC, Byrd DA, Siegel EM, Ulrich CM, Stephens WZ, Round JL.

In press, 2025

Neonatal fungi promote lifelong metabolic health through macrophage-dependent β cell development

Hill JH, Bell R, Barrios L, Baird H, Ost K, Greenewood M, Monts JK, Tracy E, Meili CH, Chiaro TR, Weis AM, Guillemin K, Beaudin AE, Murtaugh LC, Stephens WZ, Round JL.

Science 387 (6738), eadn0953

A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy

Tang WW, Battistone B, Bauer KM, Weis AM, Barba C, Fadlullah MZH, Ghazaryan A, Tran VB, Lee SH, Agir ZB, Nelson MC, Victor ES, Thibeaux A, Hernandez C, Tantalla J, Tan AC, Rao D, Williams M, Drummond MJ, Beswick EJ, Round JL, Ekiz HA, Voth WP, O'Connell RM.

Cell Reports 44 (2)

Clec12a controls colitis by tempering inflammation and restricting expansion of specific commensals

Chiaro TR*, Greenewood M*, Bauer KM, Ost KS, Stephen-Victor E, Murphy M, Weis AM, Nelson MC, Hill JH, Bell R, Voth W, Jackson T, Klag K, O’Connell RM, Stephens WZ, Round JL.

Cell Host & Microbe 33 (1), 89-103. e7

Draft genome of a human gut-derived Blautia sp. that ameliorates colitis and colitis-associated sociability deficits in mice

Murphy M, Brown D, Bell R, Weis AM, Barrios L, Stephens WZ, Round JL

Microbiology Resource Announcements 14 (1), e00726-24

2024

Draft Turicibacter sp. genome isolated from a spore-forming community in mice

Weis AM*, Klag KA*, Stephens WZ, Round JL.

Microbiology Resource Announcements 13 (8), e00385-24

Genomes of diverse Clostridia isolated from a spore forming community in mice that were associated with protection against metabolic syndrome and obesity

Weis AM*, Klag KA*, Bell R, Stephens WZ, Round JL.

Microbiology Resource Announcements 13 (7), e00351-24

Colitis reduces active social engagement in mice and is ameliorated by supplementation with human microbiota members

Brown DG, Murphy M, Caddedu R, Bell R, Weis AM, Chiaro T, Klag KA, Morgan J, Coon H, Stephens WZ, Bortolato M, Round JL.

Nature Communications 15 (1), 2769

Draft genome of a human-derived pks+ E. coli that caused spontaneous disseminated infection in a mouse

Weis AM, Matthews OJ, Mulvey MA, Round JL.

Microbiology Resource Announcements 13 (7), e00387-24

2022

CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis

Bauer KM, Nelson MC, Tang WW, Chiaro TR, D. Brown DG, Ghazaryan A, Lee S, Weis AM, Hill JH, Ramstead A, Monts J, Marvin J, Alexander M, Voth WP, Stephens WZ, Ward D, Petrey A, Round JL and O’Connell RM.

JCI insight 7 (19), e159469

2021

Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

Stephens WZ, Kubinak JL, Ghazaryan A, Bauer KM, Bell R, Buhrke K, Chiaro TR, Weis AM, Tang WW, Monts JK, Soto R, Ekiz HA, O’Connell RM, Round JL.

Cell reports 37 (5)

Microbiota-antibody interactions that regulate gut homeostasis

AM Weis, JL Round

Cell host & microbe 29 (3), 334-346

2018

Commensal regulation of T cell survival through Erdr1

Weis AM, Soto R, Round JL.

2018. Gut Microbes. Mar 15:1-17. PMID: 29543554

Graduate Work

This section is under construction….

Phylogenetic and biogeographic patterns of Vibrio parahaemolyticus strains from North America inferred from whole-genome sequence data

JJ Miller, BC Weimer, R Timme, CHM Lüdeke, JB Pettengill, DJD Bandoy, ...

Applied and environmental microbiology 87 (3), e01403-20

Insular microbiogeography: Three pathogens as exemplars

JH Kaufman, CA Elkins, M Davis, AM Weis, BC Huang, MK Mammel, ...

Current issues in molecular biology 36 (1), 89-108

Low heterozygosity is associated with vector‐borne disease in crows

AK Townsend, CC Taff, SS Wheeler, AM Weis, MG Hinton, ML Jones, ...

Ecosphere 9 (10), e02407

2020

Comparative analysis of Campylobacter isolates from wild birds and chickens using MALDI-TOF MS, biochemical testing, and DNA sequencing

SJ Lawton, AM Weis, BA Byrne, H Fritz, CC Taff, AK Townsend, ...

Journal of Veterinary Diagnostic Investigation 30 (3), 354-361

Large-scale release of 1,100 Salmonella draft genomes; resources for food safety and public health from the 100K Pathogen Genome Project.

Kong N, Davis M, Arabyan N, Huang BC, Weis AM, Chen P, … Weimer BC. 2017.

Genome Announcements. July 2017 vol. 5 no. 28 e00518-17. doi: 10.1128/genomeA.00518-17

Implication of Sialidases in Salmonella Infection: Genome Release of Sialidase Knockout Strains from Salmonella enterica Serovar Typhimurium LT2

N Arabyan, AM Weis, BC Huang, BC Weimer

Genome Announcements 5 (19), 10.1128/genomea. 00341-17

Shigella draft genomes: resources for food safety and public health

AM Weis, B Gilpin, BC Huang, N Kong, P Chen, BC Weimer

Genome Announcements 5 (16)

Automation of PacBio SMRTbell NGS library preparation for bacterial genome sequencing

SLBCWE Nguyet Kong, Whitney Ng, Kao Thao, Regina Agulto, Allison Weis ...

Standards in Genomic Sciences 12 (27)

Weis AM, Clothier KA, Huang B, Kong NT, Weimer BC.
Multidrug resistant abortive C. jejuni draft genome from Northern California. 2017.
Genome Announcements 5:e00171-17. https://doi.org/10.1128/genomeA.00171-17

Fallacy of the Unique Genome: Sequence Diversity within Single Helicobacter pylori Strains

JL Draper, LM Hansen, DL Bernick, S Abedrabbo, JG Underwood, ...

MBio 8 (1), 10.1128/mbio. 02321-16

Large-Scale Release of Campylobacter Draft Genomes: Resources for Food Safety and Public Health from the 100K Pathogen Genome Project

AM Weis, BC Huang, DB Storey, N Kong, P Chen, N Arabyan, B Gilpin, ...

Genome announcements 5 (1), 10.1128/genomea. 00925-16

Weis AM, Clothier KA, Huang BC, Kong N, Weimer BC. 2016.
Campylobacter jejuni strains that cause abortion in livestock.
Genome Announcements 4(6):e01324-16. doi: 10.1128/genomeA.01324-16.

Genomic comparison of Campylobacter spp. and their potential for zoonotic transmission between birds, primates, and livestock

AM Weis, DB Storey, CC Taff, AK Townsend, BC Huang, NT Kong, ...

Applied and Environmental Microbiology 82 (24), 7165-7175

Salmonella Degrades the Host Glycocalyx Leading to Altered Infection and Glycan Remodeling

N Arabyan, D Park, S Foutouhi, AM Weis, BC Huang, CC Williams, ...

Scientific reports 6 (1), 29525

The journey of Campylobacter: a genomic analysis of a successful zoonotic pathogen

AM Weis, BC Weimer

Atlas of Science

Draft Genome Sequences of 1,183 Salmonella Strains from the 100K Pathogen Genome Project

N Kong, M Davis, N Arabyan, BC Huang, AM Weis, P Chen, K Thao, W Ng, ...

Genome announcements 5 (28), 10.1128/genomea. 00518-17